Motif ID: TFAP2{A,C}.p2

Z-value: 2.131

Transcription factors associated with TFAP2{A,C}.p2:

NameEntrezDescription
Tcfap2a 21418 transcription factor AP-2, alpha
Tcfap2c 21420 transcription factor AP-2, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
Tcfap2achr13_-_40829082-0.591.3e-04Click!
Tcfap2cchr2_+_1723750920.492.5e-03Click!


Activity profile for motif TFAP2{A,C}.p2.

activity profile for motif TFAP2{A,C}.p2


Sorted Z-values histogram for motif TFAP2{A,C}.p2

Sorted Z-values for motif TFAP2{A,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2{A,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Description
chr2_-_154395469 8.180 NM_007891
E2f1
E2F transcription factor 1
chr2_+_156301543 7.739 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr2_+_119568028 7.279 NM_146125
Itpka
inositol 1,4,5-trisphosphate 3-kinase A
chr2_+_146047656 6.646 NM_016889
Insm1
insulinoma-associated 1
chr10_-_120913138 6.328 NM_138956
Rassf3
Ras association (RalGDS/AF-6) domain family member 3
chr14_-_103381744 5.808 NM_177715
Kctd12
potassium channel tetramerisation domain containing 12
chr1_+_59538966 5.608 NM_008057
Fzd7
frizzled homolog 7 (Drosophila)
chr4_+_8617613 5.590 Chd7
chromodomain helicase DNA binding protein 7
chr6_-_115944822 5.538 NM_026376
Plxnd1
plexin D1
chr4_+_53453302 5.506 Slc44a1
solute carrier family 44, member 1
chr5_+_89315839 5.106 Slc4a4
solute carrier family 4 (anion exchanger), member 4
chr4_-_133054355 4.902 NM_001081156
Trnp1
TMF1-regulated nuclear protein 1
chr5_+_37259780 4.733 NM_172994
Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr15_-_36538288 4.583 Pabpc1
poly(A) binding protein, cytoplasmic 1
chr7_+_52419317 4.443 Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr17_-_88197333 4.269 NM_199251
Kcnk12
potassium channel, subfamily K, member 12
chr11_-_6375845 4.179 NM_011221
Purb
purine rich element binding protein B
chr16_+_33684551 4.050 NM_175256
Heg1
HEG homolog 1 (zebrafish)
chr17_+_87362612 3.843 Rhoq
ras homolog gene family, member Q
chr6_-_53770406 3.822 Tril
TLR4 interactor with leucine-rich repeats
chr3_-_8666985 3.814 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr5_+_37633317 3.780 NM_001136058
Crmp1
collapsin response mediator protein 1
chr6_-_87931475 3.736 NM_198622
H1fx
H1 histone family, member X
chr12_+_109572514 3.716 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr2_+_162880370 3.714 NM_008652
Mybl2
myeloblastosis oncogene-like 2
chr7_-_71083734 3.565 NM_021366
Klf13
Kruppel-like factor 13
chr14_+_122874598 3.525 NM_009574
Zic2
zinc finger protein of the cerebellum 2
chr1_+_193542261 3.433 NM_001134829
Lpgat1
lysophosphatidylglycerol acyltransferase 1
chr8_-_113917651 3.397 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr14_+_35124004 3.397 Glud1
glutamate dehydrogenase 1
chr2_-_77654669 3.379 NM_178723
Zfp385b
zinc finger protein 385B
chr8_-_72498125 3.368 Gatad2a
GATA zinc finger domain containing 2A
chrX_+_70918446 3.348 NM_001142809
NM_001142810
NM_133987
Slc6a8


solute carrier family 6 (neurotransmitter transporter, creatine), member 8


chr17_+_81343933 3.310 NM_026516
Tmem178
transmembrane protein 178
chr14_-_121778399 3.297 NM_145465
Stk24
serine/threonine kinase 24 (STE20 homolog, yeast)
chr2_-_29701764 3.250 Gm3088
predicted gene 3088
chr10_+_93103715 3.240 NM_021320
Ntn4
netrin 4
chr4_+_129662110 3.205 Bai2
brain-specific angiogenesis inhibitor 2
chr8_-_72498210 3.175 NM_001113346
Gatad2a
GATA zinc finger domain containing 2A
chr11_-_4847968 3.146 NM_010904
Nefh
neurofilament, heavy polypeptide
chr2_-_91803660 3.135 NM_138306
Dgkz
diacylglycerol kinase zeta
chr12_-_77811119 3.125 Spnb1
spectrin beta 1
chrX_+_20265522 3.059 Cdk16
cyclin-dependent kinase 16
chr4_+_126846429 3.050 NM_198618
Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr5_-_53604536 2.974 Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr11_-_94538693 2.961 NM_145828
Xylt2
xylosyltransferase II
chr2_+_27532692 2.910 NM_011305
Rxra
retinoid X receptor alpha
chr2_+_27741864 2.883 NM_015734
Col5a1
collagen, type V, alpha 1
chr7_+_120909680 2.881 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr8_-_89996089 2.848 Cbln1
cerebellin 1 precursor protein
chr7_-_31911884 2.848 NM_011322
Scn1b
sodium channel, voltage-gated, type I, beta
chr2_+_129419252 2.841 Sirpa
signal-regulatory protein alpha
chr4_+_53453277 2.817 NM_001159633
NM_133891
Slc44a1

solute carrier family 44, member 1

chr7_+_52419289 2.805 NM_182993
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr18_+_35989376 2.751 NM_133687
Cxxc5
CXXC finger 5
chr9_+_51856305 2.733 Rdx
radixin
chr17_-_33918382 2.700 Angptl4
angiopoietin-like 4
chr7_+_51846254 2.683 NM_008422
Kcnc3
potassium voltage gated channel, Shaw-related subfamily, member 3
chr12_+_114336416 2.683 NM_054081
Mta1
metastasis associated 1
chr9_+_45820886 2.680 NM_027498
Sik3
SIK family kinase 3
chr9_-_91259829 2.679 Zic1
zinc finger protein of the cerebellum 1
chr5_-_115140869 2.613 NM_019821
Gltp
glycolipid transfer protein
chr3_+_87710282 2.585 Hdgf
hepatoma-derived growth factor
chr3_+_89577436 2.585 NM_027315
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chr1_-_137584672 2.560 Nav1
neuron navigator 1
chr3_+_117278144 2.549 NM_029425
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr1_-_134439436 2.537 Cntn2
contactin 2
chr16_+_91270009 2.536 NM_016968
Olig1
oligodendrocyte transcription factor 1
chr14_+_9046655 2.528 NM_027782
Kctd6
potassium channel tetramerisation domain containing 6
chr14_-_19071459 2.492 NM_011584
Nr1d2
nuclear receptor subfamily 1, group D, member 2
chr2_-_93797176 2.483 NM_001145034
Gm13889
predicted gene 13889
chrX_+_148578716 2.478 NM_001114664
Iqsec2
IQ motif and Sec7 domain 2
chr7_+_114514258 2.432 NM_021889
Syt9
synaptotagmin IX
chr5_+_37633353 2.431 Crmp1
collapsin response mediator protein 1
chrX_+_20265590 2.419 NM_011049
Cdk16
cyclin-dependent kinase 16
chr6_-_23789259 2.406 NM_153163
Cadps2
Ca2+-dependent activator protein for secretion 2
chr5_+_37259906 2.379 Ppp2r2c
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr15_-_78994753 2.368 NM_011437
Sox10
SRY-box containing gene 10
chr6_+_108163089 2.363 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr2_+_164793698 2.360 Slc12a5
solute carrier family 12, member 5
chr7_+_73007017 2.354 NM_011048
Pcsk6
proprotein convertase subtilisin/kexin type 6
chr7_-_38892432 2.344 NM_007633
Ccne1
cyclin E1
chr8_-_87323958 2.343 Nfix
nuclear factor I/X
chr10_-_115910578 2.341 NM_021452
Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr18_+_58038278 2.327 NM_009194
Slc12a2
solute carrier family 12, member 2
chr8_-_125201971 2.325 NM_001109873
NM_177289
Cbfa2t3

core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)

chr11_-_97490978 2.323 NM_175332
E130012A19Rik
RIKEN cDNA E130012A19 gene
chr11_-_69734369 2.319 NM_001166592
NM_001166594
Eif5a

eukaryotic translation initiation factor 5A

chr3_-_8667013 2.302 NM_010423
Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr11_+_94189303 2.287 NM_027799
NM_146024
Ankrd40

ankyrin repeat domain 40

chr9_+_89804723 2.282 Rasgrf1
RAS protein-specific guanine nucleotide-releasing factor 1
chr7_+_109416314 2.274 NM_009287
Stim1
stromal interaction molecule 1
chr14_-_26588341 2.272 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr3_+_121948541 2.270 Gclm
glutamate-cysteine ligase, modifier subunit
chr15_+_27396405 2.248 NM_020332
Ank
progressive ankylosis
chr4_+_8617550 2.229 Chd7
chromodomain helicase DNA binding protein 7
chr6_-_119988624 2.222 NM_001185020
NM_001185021
NM_198703
Wnk1


WNK lysine deficient protein kinase 1


chr15_-_86016070 2.217 Cerk
ceramide kinase
chr6_-_125263750 2.188 NM_010736
Ltbr
lymphotoxin B receptor
chr10_-_115910911 2.173 Kcnmb4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr9_-_57110250 2.167 NM_028820
1700017B05Rik
RIKEN cDNA 1700017B05 gene
chr16_+_20733199 2.151 NM_009893
Chrd
chordin
chr4_+_129662284 2.147 NM_173071
Bai2
brain-specific angiogenesis inhibitor 2
chrX_-_138740574 2.142 Kcne1l
potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene
chr10_-_8238569 2.123 NM_177387
Ust
uronyl-2-sulfotransferase
chr4_+_46052115 2.116


chr3_-_8666930 2.113 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr19_+_5741862 2.107 Ltbp3
latent transforming growth factor beta binding protein 3
chr12_+_33505364 2.096 Nampt
nicotinamide phosphoribosyltransferase
chr2_+_92024338 2.094 NM_138755
Phf21a
PHD finger protein 21A
chr5_+_115956682 2.067 NM_011223
NM_133915
Pxn

paxillin

chr11_+_100436283 2.062 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_-_65427840 2.059 NM_153119
Plekho2
pleckstrin homology domain containing, family O member 2
chr1_+_182260606 2.046 NM_001081175
Itpkb
inositol 1,4,5-trisphosphate 3-kinase B
chr11_-_106134024 2.042 NM_001130187
Smarcd2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
chr2_-_165060188 2.042 NM_174988
Cdh22
cadherin 22
chr2_+_129418930 2.035 NM_001177647
NM_007547
Sirpa

signal-regulatory protein alpha

chr17_-_45686604 2.029 NM_001013749
Tmem151b
transmembrane protein 151B
chr14_+_34736772 2.002 NM_145741
Gdf10
growth differentiation factor 10
chrX_-_71269083 1.997 Irak1
interleukin-1 receptor-associated kinase 1
chr4_+_15192892 1.997 NM_181401
Tmem64
transmembrane protein 64
chr5_+_102194207 1.984 Cds1
CDP-diacylglycerol synthase 1
chr2_-_25978296 1.977 Nacc2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr9_+_45820921 1.975 Sik3
SIK family kinase 3
chr10_-_41996462 1.973 NM_019740
Foxo3
forkhead box O3
chr7_+_120909625 1.971 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr6_-_71390481 1.967 Rmnd5a
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr15_+_100058310 1.965 Atf1
activating transcription factor 1
chr10_-_6979959 1.956 Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr19_-_7062118 1.956 NM_001185164
NM_011697
Vegfb

vascular endothelial growth factor B

chr2_-_150730357 1.955 Abhd12
abhydrolase domain containing 12
chr17_-_10512217 1.948 NM_001159516
NM_001159517
NM_021881
Qk


quaking


chr16_+_4594703 1.942 NM_031184
Glis2
GLIS family zinc finger 2
chr4_-_47004585 1.921 NM_001081141
Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr9_-_63605745 1.890 NM_016769
Smad3
MAD homolog 3 (Drosophila)
chr2_+_35477498 1.877 NM_001114124
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr13_+_64263131 1.875 NM_019986
Habp4
hyaluronic acid binding protein 4
chr10_-_80024245 1.873 NM_025852
Rexo1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)
chr9_-_107569654 1.872 NM_023805
Slc38a3
solute carrier family 38, member 3
chr5_-_135223110 1.868 NM_007925
Eln
elastin
chr19_+_46576230 1.849 Trim8
tripartite motif-containing 8
chr13_+_23830944 1.844 Hist1h1c
histone cluster 1, H1c
chr10_-_6980199 1.837 NM_133485
Ppp1r14c
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr19_+_46471385 1.834 NM_001025391
NM_015752
Sufu

suppressor of fused homolog (Drosophila)

chr12_-_77810949 1.833 Spnb1
spectrin beta 1
chr11_+_101329457 1.827 Rnd2
Rho family GTPase 2
chr17_+_30142111 1.824 Zfand3
zinc finger, AN1-type domain 3
chr7_+_129432810 1.809 Prkcb
protein kinase C, beta
chr3_+_17954500 1.803 Bhlhe22
basic helix-loop-helix family, member e22
chr19_+_21346734 1.797 NM_009551
Zfand5
zinc finger, AN1-type domain 5
chr5_+_109123159 1.793 NM_001164259
NM_054071
Fgfrl1

fibroblast growth factor receptor-like 1

chr13_+_23830671 1.786 NM_015786
Hist1h1c
histone cluster 1, H1c
chr10_-_76880977 1.784 Adarb1
adenosine deaminase, RNA-specific, B1
chr11_-_69734838 1.780 NM_001166589
NM_001166591
NM_181582
Eif5a


eukaryotic translation initiation factor 5A


chr2_+_25227840 1.778 NM_001081085
2010317E24Rik
RIKEN cDNA 2010317E24 gene
chr17_-_45732442 1.773 Slc29a1
solute carrier family 29 (nucleoside transporters), member 1
chrX_+_159198302 1.756 NM_009031
Rbbp7
retinoblastoma binding protein 7
chr2_+_164595447 1.754 Ube2c
ubiquitin-conjugating enzyme E2C
chrX_-_154481041 1.749 NM_177751
Cnksr2
connector enhancer of kinase suppressor of Ras 2
chr6_+_29867012 1.742 NM_001037740
NM_177204
Fam40b

family with sequence similarity 40, member B

chr4_+_46463917 1.734 NM_130889
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr17_+_29627697 1.733 Pim1
proviral integration site 1
chr7_+_129432585 1.724 NM_008855
Prkcb
protein kinase C, beta
chr3_-_120965803 1.722 Tmem56
transmembrane protein 56
chr11_-_33103458 1.709 NM_019916
Tlx3
T-cell leukemia, homeobox 3
chr8_-_83262881 1.680 Smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr7_-_20281956 1.679


chr19_-_12869863 1.667 Zfp91
zinc finger protein 91
chr8_-_89996474 1.662 NM_019626
Cbln1
cerebellin 1 precursor protein
chr4_+_128404814 1.656 NM_001195083
Phc2
polyhomeotic-like 2 (Drosophila)
chr16_+_4594742 1.652 Glis2
GLIS family zinc finger 2
chr18_+_75527015 1.648 NM_001042660
Smad7
MAD homolog 7 (Drosophila)
chr6_-_53770687 1.648 NM_025817
Tril
TLR4 interactor with leucine-rich repeats
chr13_+_49282844 1.643 NM_013610
Ninj1
ninjurin 1
chr3_-_101408495 1.640 NM_144900
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr7_-_86611065 1.638 NM_017462
Polg
polymerase (DNA directed), gamma
chr9_+_113840232 1.633 Ubp1
upstream binding protein 1
chr14_+_122874625 1.631 Zic2
zinc finger protein of the cerebellum 2
chr2_+_121115337 1.627 NM_032393
Mtap1a
microtubule-associated protein 1 A
chr16_+_30599808 1.624 NM_177632
Fam43a
family with sequence similarity 43, member A
chr5_+_115879617 1.618 NM_008629
Msi1
Musashi homolog 1(Drosophila)
chr17_-_27650285 1.616 Grm4
glutamate receptor, metabotropic 4
chr14_-_79701303 1.615 NM_025427
1190002H23Rik
RIKEN cDNA 1190002H23 gene
chr11_+_43342241 1.615 NM_001045530
Ccnjl
cyclin J-like
chr12_-_52792851 1.614 NM_001172098
NM_052973
Strn3

striatin, calmodulin binding protein 3

chr8_+_82163574 1.610 NM_001081164
Otud4
OTU domain containing 4
chr9_-_63605917 1.610 Smad3
MAD homolog 3 (Drosophila)
chr13_+_54472806 1.607 Cplx2
complexin 2
chr14_+_35123922 1.601 Glud1
glutamate dehydrogenase 1
chr8_-_87324043 1.599 NM_001081982
NM_010906
Nfix

nuclear factor I/X

chr12_+_3806955 1.597 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr10_+_80599284 1.596 Zbtb7a
zinc finger and BTB domain containing 7a
chr17_-_10512094 1.595 Qk
quaking
chr8_+_107064705 1.595 NM_053070
Car7
carbonic anhydrase 7
chr4_+_106584400 1.595 Ssbp3
single-stranded DNA binding protein 3
chr2_+_25118144 1.594 Tprn
taperin
chr11_+_60351159 1.588 NM_172943
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr13_-_23714425 1.587 NM_015787
Hist1h1e
histone cluster 1, H1e
chr2_+_156665812 1.584 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr17_+_24607348 1.581 NM_025954
Pgp
phosphoglycolate phosphatase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment p-value GO term description
2.16 2.99e-12 GO:0007275 multicellular organismal development
2.01 5.10e-12 GO:0031323 regulation of cellular metabolic process
2.08 7.48e-12 GO:0032502 developmental process
2.20 1.55e-11 GO:0048856 anatomical structure development
1.99 2.01e-11 GO:0080090 regulation of primary metabolic process
1.50 2.44e-11 GO:0065007 biological regulation
1.90 3.43e-11 GO:0019222 regulation of metabolic process
2.26 6.66e-11 GO:0048731 system development
2.24 4.74e-10 GO:0006355 regulation of transcription, DNA-dependent
1.48 8.16e-10 GO:0050789 regulation of biological process
2.20 1.42e-09 GO:0051252 regulation of RNA metabolic process
2.09 1.75e-09 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.07 2.12e-09 GO:0009889 regulation of biosynthetic process
2.07 2.57e-09 GO:0031326 regulation of cellular biosynthetic process
1.92 2.75e-09 GO:0060255 regulation of macromolecule metabolic process
2.13 2.89e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.06 3.22e-09 GO:0051171 regulation of nitrogen compound metabolic process
2.10 4.48e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.48 9.94e-09 GO:0050794 regulation of cellular process
2.06 1.04e-08 GO:0010468 regulation of gene expression
2.31 8.76e-08 GO:0006351 transcription, DNA-dependent
2.31 9.47e-08 GO:0032774 RNA biosynthetic process
2.49 3.16e-07 GO:0009653 anatomical structure morphogenesis
2.26 3.56e-07 GO:0048513 organ development
2.79 6.83e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.05 2.52e-06 GO:0048523 negative regulation of cellular process
1.97 4.65e-06 GO:0048519 negative regulation of biological process
3.22 5.14e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.87 5.60e-06 GO:0048518 positive regulation of biological process
1.26 5.92e-06 GO:0009987 cellular process
3.17 7.49e-06 GO:0051253 negative regulation of RNA metabolic process
1.96 8.15e-06 GO:0016070 RNA metabolic process
2.99 1.89e-05 GO:0010629 negative regulation of gene expression
3.61 2.59e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.89 3.49e-05 GO:0009059 macromolecule biosynthetic process
1.86 4.00e-05 GO:0010467 gene expression
3.63 4.38e-05 GO:0032583 regulation of gene-specific transcription
1.73 7.16e-05 GO:0009058 biosynthetic process
2.88 7.34e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.98 7.36e-05 GO:0048869 cellular developmental process
1.75 7.57e-05 GO:0044249 cellular biosynthetic process
2.85 9.77e-05 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.84 1.05e-04 GO:0051172 negative regulation of nitrogen compound metabolic process
1.86 1.18e-04 GO:0034645 cellular macromolecule biosynthetic process
1.84 1.23e-04 GO:0048522 positive regulation of cellular process
1.97 1.26e-04 GO:0030154 cell differentiation
2.73 1.72e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.52 1.89e-04 GO:0032501 multicellular organismal process
1.43 2.11e-04 GO:0044237 cellular metabolic process
2.74 2.47e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.40 2.83e-04 GO:0050793 regulation of developmental process
3.11 2.87e-04 GO:0072358 cardiovascular system development
3.11 2.87e-04 GO:0072359 circulatory system development
2.66 2.99e-04 GO:0009890 negative regulation of biosynthetic process
1.53 3.14e-04 GO:0044260 cellular macromolecule metabolic process
1.74 3.45e-04 GO:0016043 cellular component organization
2.26 4.95e-04 GO:0007399 nervous system development
3.61 6.15e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.74 6.63e-04 GO:0090304 nucleic acid metabolic process
1.96 6.88e-04 GO:0065008 regulation of biological quality
1.62 8.37e-04 GO:0034641 cellular nitrogen compound metabolic process
2.45 9.43e-04 GO:0009888 tissue development
1.69 1.09e-03 GO:0071840 cellular component organization or biogenesis
2.50 1.25e-03 GO:0009790 embryo development
1.59 1.47e-03 GO:0006807 nitrogen compound metabolic process
2.06 1.48e-03 GO:0023051 regulation of signaling
1.45 2.80e-03 GO:0043170 macromolecule metabolic process
1.62 3.48e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 4.27e-03 GO:0044238 primary metabolic process
1.79 4.52e-03 GO:0071842 cellular component organization at cellular level
1.33 5.59e-03 GO:0008152 metabolic process
1.96 7.72e-03 GO:0051239 regulation of multicellular organismal process
2.39 9.81e-03 GO:0045595 regulation of cell differentiation
2.08 9.82e-03 GO:0009966 regulation of signal transduction
2.21 1.02e-02 GO:0031324 negative regulation of cellular metabolic process
2.15 1.10e-02 GO:0009892 negative regulation of metabolic process
2.20 1.12e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.73 1.32e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.89 1.36e-02 GO:0048583 regulation of response to stimulus
4.02 1.54e-02 GO:0032582 negative regulation of gene-specific transcription
2.36 1.70e-02 GO:0045893 positive regulation of transcription, DNA-dependent
2.60 1.92e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.19 2.24e-02 GO:0035295 tube development
2.33 2.27e-02 GO:0051254 positive regulation of RNA metabolic process
1.70 2.37e-02 GO:0071841 cellular component organization or biogenesis at cellular level
2.28 2.55e-02 GO:0016310 phosphorylation
2.09 2.62e-02 GO:0010646 regulation of cell communication
2.98 3.41e-02 GO:0048729 tissue morphogenesis
2.24 3.43e-02 GO:0010628 positive regulation of gene expression
3.35 3.69e-02 GO:0007507 heart development
2.10 4.03e-02 GO:0006796 phosphate metabolic process
2.09 4.21e-02 GO:0006793 phosphorus metabolic process
4.16 4.63e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
2.17 4.84e-02 GO:0010557 positive regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment p-value GO term description
1.33 8.35e-09 GO:0005622 intracellular
1.65 1.86e-08 GO:0005634 nucleus
1.32 4.75e-08 GO:0044424 intracellular part
1.36 4.15e-07 GO:0043226 organelle
1.35 1.12e-06 GO:0043229 intracellular organelle
1.36 1.01e-05 GO:0043231 intracellular membrane-bounded organelle
1.36 1.20e-05 GO:0043227 membrane-bounded organelle
1.17 1.52e-05 GO:0005623 cell
1.17 1.52e-05 GO:0044464 cell part
17.95 1.34e-04 GO:0031519 PcG protein complex
2.87 1.36e-04 GO:0043005 neuron projection
2.16 8.05e-04 GO:0042995 cell projection
2.86 9.16e-04 GO:0045202 synapse
2.45 2.83e-03 GO:0044451 nucleoplasm part
1.49 5.27e-03 GO:0071944 cell periphery
3.07 5.76e-03 GO:0044456 synapse part
1.49 6.99e-03 GO:0005886 plasma membrane
2.06 9.14e-03 GO:0005654 nucleoplasm
1.78 9.53e-03 GO:0070013 intracellular organelle lumen
1.85 9.99e-03 GO:0031981 nuclear lumen
1.78 1.00e-02 GO:0043233 organelle lumen
1.75 1.13e-02 GO:0044428 nuclear part
3.00 1.29e-02 GO:0043025 neuronal cell body
1.75 1.67e-02 GO:0031974 membrane-enclosed lumen
1.55 1.76e-02 GO:0043234 protein complex
4.92 1.94e-02 GO:0034703 cation channel complex
2.86 2.33e-02 GO:0044297 cell body
2.99 3.58e-02 GO:0030425 dendrite
5.94 3.65e-02 GO:0008076 voltage-gated potassium channel complex
5.94 3.65e-02 GO:0034705 potassium channel complex

Gene overrepresentation in function category:

enrichment p-value GO term description
1.85 1.59e-17 GO:0005515 protein binding
1.42 2.26e-14 GO:0005488 binding
2.55 5.13e-12 GO:0003677 DNA binding
2.10 7.66e-10 GO:0003676 nucleic acid binding
3.03 2.31e-07 GO:0001071 nucleic acid binding transcription factor activity
3.03 2.31e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.73 2.59e-06 GO:0043167 ion binding
1.72 4.43e-06 GO:0043169 cation binding
1.72 5.02e-06 GO:0046872 metal ion binding
2.27 7.37e-06 GO:0008270 zinc ion binding
2.08 3.14e-05 GO:0046914 transition metal ion binding
2.53 3.29e-05 GO:0030528 transcription regulator activity
2.61 8.42e-04 GO:0043565 sequence-specific DNA binding
3.45 9.43e-04 GO:0016564 transcription repressor activity
2.35 1.13e-03 GO:0019899 enzyme binding
3.27 2.02e-03 GO:0016563 transcription activator activity
5.86 2.43e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
6.32 3.75e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
3.79 6.73e-03 GO:0000975 regulatory region DNA binding
3.79 6.73e-03 GO:0001067 regulatory region nucleic acid binding
3.79 6.73e-03 GO:0044212 transcription regulatory region DNA binding
3.64 1.99e-02 GO:0003682 chromatin binding
2.44 3.70e-02 GO:0019904 protein domain specific binding
3.17 4.62e-02 GO:0019901 protein kinase binding